Prognostic factors for polyp recurrence in chronic sinusitis

Chronic rhinosinusitis with nasal polyps is frequently managed with endoscopic sinus surgery (ESS). Prior studies describe individual clinical variables and eosinophil density measures as prognostic for

Polyp recurrence (PR) was found in 39.4% of patients with CRSwNP s/p endoscopic surgery.

Polyp recurrence (PR) was associated with:

- modified Lund-Mackay (MLM) radiographic score (MLM)
- asthma
- eosinophil cationic protein
- anti–double-stranded DNA IgG
- IL-5

A combined model comprised of eosinophil cationic protein, IL-5, pre-ESS MLM, asthma, and anti–double-stranded DNA IgG could accurately predict polyp recurrence (PR).

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https://www.jacionline.org/article/S0091-6749(22)00343-8/fulltext