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Lebrikizumab (Ebglyss) Approval: A New Treatment Option for Atopic Dermatitis

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The landscape of atopic dermatitis (AD) treatment has seen significant advancements in recent years. The most recent approval of a new thera...

SABA/ICS prn combo for asthma: AIRSUPRA (albuterol/budesonide)

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As of January 2023, AIRSUPRA (albuterol/budesonide), has been approved in the US for the as-needed treatment or prevention of bronchoconstri...

Allergic diseases and sleep problems in children

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Allergic rhinitis was associated with a broad range of sleep problems and to a lesser extent in children with asthma and least in children w...

Add-on etanercept as a treatment for Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN)

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Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) is a severe cutaneous adverse reaction to drugs. The disease carries considera...

Against the hygiene hypothesis as the cause of allergic diseases

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The article argues against the hygiene hypothesis for causation of allergic diseases: https://www.annallergy.org/article/S1081-1206(22)00585...

Prognostic factors for polyp recurrence in chronic sinusitis

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Chronic rhinosinusitis with nasal polyps is frequently managed with endoscopic sinus surgery (ESS). Prior studies describe individual clinic...

Blood endotypic signatures in atopic dermatitis

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Atopic dermatitis (AD) is the most common chronic inflammatory skin disease. AD can be very challenging to manage. AD is characterized by: ...

Eosinophilic gastrointestinal diseases: updated nomenclature

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Eosinophilic gastrointestinal (GI) diseases (EGIDs) are characterized by tissue eosinophilia and symptoms of esophageal or GI dysfunction. ...

Chronic rhinosinusitis: Future treatments review in JACI

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Chronic rhinosinusitis (CRS) has a major clinical impact and affects 10% of the US population. CRS presents with 2 major phenotypes : - CRS ...

T2 inflammation biomarkers and cytokines

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T2 inflammation is characterized by elevations in: - absolute peripheral or sputum eosinophil counts - levels of IgE (total and allergen-spe...