Allergy Notes, Evidence-based Information by Board-certified Physicians

Asthma and allergy genetic testing by 23andMe

Genes that contribute to lung function decline in asthma: ADAM33, ESR1, PLAUR, and VEGF

Atopic march (allergic march) - the progression from atopic dermatitis to asthma - mediated by filaggrin defect?

Living on a farm and parental allergen sensitization reflected in utero at gene expression level

Chromosome 11q13.5 variant associated with atopic dermatitis - in addition to filaggrin (FLG) mutations

2010 Update on genetics of atopic dermatitis: Scratching the surface

Defects of structural protein filaggrin as a risk factor for atopic dermatitis

In-utero exposures (diet, microbial products, smoking) may program the susceptibility to asthma and allergic disease

Filaggrin (FLG) mutations increase risk of severe atopic dermatitis and asthma

TBX21 gene variants (responsible for T-bet) may increase childhood asthma risk

2 new asthma susceptibility genes: ORMDL3 and CHI3L1