Dr Marc Riedl discussed skin allergy updates:
Dapsone seems to help with chronic urticaria, especially with regards to itch and reduction of hives with minimal AEs (some Hgb decrease).
In a sulfasalazine study in chronic urticaria, 20% of sulfasalazine therapy patients had AEs (mainly hematologic), 2 serious AEs (leukopenia and rhabdomyolysis) but there was some efficacy.
In a study of high dose Vitamin D in chronic urticaria, patients were on Zyrtec, Zantac and Singulair plus high-dose, low dose Vit D and control. There was some improvement seen especially in high dose Vit D treated patients but results were not quite statistically significant.
Epidemiology study on angioedema from J Int Med: 1700 patients with recurrent angioedema, 61% did not have allergy or autoimmune disease. Idiopathic was the most common form of angioedema, not allergic or autoimmune, C1-INH deficiency was the second most common. ACEI induced angioedema was probably underestimated in their study
Dupilumab (anti-IL4Ra monoclonal) for atopic dermatitis - NEJM. Dupilumab caused trend toward normalization of gene expression in treated patients, with no adverse effects.
Dr Marc Riedl also showed the Pediatrics article with a SINGLE case of contact derm due to nickel allergy from iPad. http://t.co/gTMfmBJHvu
Wet wipes can be a source for contact dermatitis due to preservative MCI/MI.
This is a Twitter summary from 2014 #ACAAI meeting. The post is a part of series. See the rest here: http://allergynotes.blogspot.com/search/label/ACAAI
The Twitter summary was made possible by @MatthewBowdish
Several allergists did a great job posting updates from the 2014 meeting of the #ACAAI. I used the website “All My Tweets” to review the tweets. For comparison, here are the tweets from previous #ACAAI meetings (scroll down the page for the past years): http://allergynotes.blogspot.com/search/label/ACAAI