Top articles about asthma in April 2012

Here are my suggestions for some of the top articles about asthma in April 2012:

The journal of Clinical and Experimental Allergy has a special issue devoted to the topic of severe asthma. Here are some selected articles from that issue:

Pathogenesis of severe asthma

What is role of allergy in severe asthma?

Asthma exacerbations are multi-component events. Each exacerbation represents an opportunity to assess and target treatment to the domains of airway pharmacotherapy, self-management behaviour, risk factors, and relevant co-morbidities.

Patients with severe asthma are best investigated and managed with a multidisciplinary team

What are the future treatments for severe asthma?

Non-atopic males with adult onset asthma are at higher risk of persistent airflow limitation. Amongst patients with adult onset asthma, non-atopic male patients are at increased risk of accelerated decline in lung function.

No difference between using Symbicort vs. nebulized salbutamol as reliever for the first 15 minutes post intervention

Approx. 9% of U.S. population has asthma - 9% of adult asthmatics have aspirin-exacerbated respiratory disease (AERD)

Percutaneous Vagus Nerve Stimulation (VNS) for Treatment of Acute Asthma Exacerbations improves FEV1 and dyspnea. 25 subjects were enrolled, 1 had minor bleeding from the procedure, and 1 had a hematoma and withdrew prior to VNS. VNS requires percutaneous placement of an electrode near the right carotid sheath and 60 minutes of VNS

Asthma remains the most common health problem among elite athletes. "Regular, moderate exercise can improve your immune system, which can also help avoid asthma attacks"

Combination therapy (LABAs plus ICS, single inhaler) is associated with a decreased risk of serious asthma-related events. Combination therapy (LABA/ICS) should be applied to all patients with moderate to severe asthma

The articles were selected from my Twitter and Google Reader streams.

Comments from Twitter:

Dr John Weiner @AllergyNet: Nice to recap these articles. Thank you

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