Immunostimulant Broncho-Vaxom (OM-85 BV) prevents wheezing attacks in preschool children

The effect of the immunostimulant OM-85 BV was assessed in preventing acute respiratory tract illnesses (ARTIs)-provoked wheezing attacks in preschool children with recurrent wheezing. OM-85 BV (Broncho-Vaxom) was provided by OM Pharma, Geneva, Switzerland. It is not a new drug and it has been available in Europe for more than 30 years. OM-85 BV consists of extracts of 8 types of bacteria thought to be important in respiratory infections. It is administered orally.

One capsule for children contains: 3,5 mg of lyophilized bacterial lysates of Haemophilus influenzae, Diplococcus pneumoniae, Klebsiella pneumoniae and ozaenae, Staphylococcus aureus, Streptococcus pyogenes and viridans, Neisseria catarrhalis.

A randomized, double-blind study included 75 children with recurrent wheezing who were 1 to 6 years old. They were given either OM-85 BV or a placebo (1 capsule per day for 10 days each month for 3 months).

Subjects given OM-85 BV had a 38% reduction in the rate of wheezing attacks.

The main difference between the OM-85 BV and placebo groups was a reduction the number of ARTIs. The duration of each wheezing attack was 2 days shorter in the group given OM-85 BV.

Administration of OM-85 BV (Broncho-Vaxom) reduced the rate and duration of wheezing attacks in preschool children with ARTIs.

Broncho-Vaxom is not yet available in the U.S.A. or Canada.


The immunostimulant OM-85 BV prevents wheezing attacks in preschool children. J Allergy Clin Immunol. 2010 Oct;126(4):763-9.


Comments from Facebook:

Kay Walker: Sounds ideal for kids & others! As a kid, I caught EVERY germ within 100kms, they ALWAYS developed into wheezes that developed into bronchitis/pneumonia/pleurisy & eventually, adrenaline injections (that's all there was). If it worked it would have changed my life totally. Must investigate!

1 comment:

  1. Anonymous10/19/2012

    It really does work. My daughter showed low IgA and IgG and her immune system was very sensitive especially after recurrent PFAPA episodes. We had her tested every 15 days and the improvement was spectacular. She was a kid that was administered antibiotics as frequently as 5 times in six months. She never had to take any antibiotic since we started the Broncho Vaxom treatment at the age of 3,5. She now is 6 years old.