6 endotypes of chronic rhinitis

6 endotypes of chronic rhinitis with different inflammatory patterns, which may help in delivering individualized treatment:

1. 38.6% were diagnosed as allergic rhinitis (AR) without asthma, with positive results for local eosinophils and high levels of local and serum IgE.

2. 13.5% as AR with asthma, with positive results for local eosinophils and high levels of local and serum IgE.

3. 18.6% were diagnosed as nonallergic rhinitis with eosinophilia syndrome (NARES) without asthma, with positive result for local eosinophils, and negative results for both local and serum IgE.

4. 4.6% were diagnosed as local allergic rhinitis (LAR) and showed positive results for local eosinophils and local IgE, but negative results for serum IgE

5. 5.0% as NARES with asthma, with positive result for local eosinophils, and negative results for both local and serum IgE.

6. 19.7% were diagnosed as idiopathic rhinitis (IR) because of high symptoms scores, but negative findings for local eosinophils, local IgE and serum IgE.

References:

Endotypes of chronic rhinitis: a cluster analysis study - Meng - - Allergy - Wiley Online Library https://buff.ly/2RgdUwO