Allergic rhinitis lowers risk of coronary heart disease, cerebrovascular disease and all-cause mortality

This large retrospective study included 100,000 patients at Kaiser Permanente Southern California.

Patients with physician-diagnosed allergic rhinitis had significantly lower risk for myocardial infarction (HR, 0.63), all coronary heart disease (CHD) (HR, 0.81), cerebrovascular disease (CVD) (HR, 0.67), and all-cause mortality (HR, 0.42). Patients with positive sIgE test result also had a decreased risk of all CHD but no association with cerebrovascular events and all-cause mortality.

Multiple studies confirm the association: patients with rhinitis have a lower risk for heart disease

Patients with allergic rhinitis have a decreased risk of cardiovascular events.

Why do patients with rhinitis have a lower risk for heart disease?

Patients with rhinitis have nearly twice as many visits for any medical diagnosis compared with patients without rhinitis supporting increased use of medical care as a plausible explanation of the observed mortality benefit.

Patients treated for their AR with an intranasal steroid and an oral antihistamine had a reduction in their systolic blood pressure and decreased highly sensitive C-reactive protein level. Treating AR symptoms may have some effect on these ASCVD risk factors.


Association of allergic rhinitis, coronary heart disease, cerebrovascular disease, and all-cause mortality - Annals of Allergy, Asthma & Immunology, August 2016

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