Respiratory allergy caused by house dust mites: Inhaled mite aeroallergens are unusually virulent (2015 review)

The house dust mite (HDM) is a major perennial allergen source and a significant cause of allergic asthma. However, awareness of the condition remains generally low.

Prevalence data for HDM allergen sensitization vary from 65 to 130 million persons in the general population worldwide to as many as 50% among asthmatic patients. Inhaled mite aeroallergens are unusually virulent: they are able to activate both the adaptive and innate immune responses. Translation of silent sensitization into symptomatic disease is still incompletely understood.

Improved understanding of HDMs, their allergens, and their microhabitats will enable development of more effective outcomes for patients with HDM allergy.

References:

Respiratory allergy caused by house dust mites: What do we really know? Moisés A. Calderón et al. JACI 2015, free full text.
http://www.jacionline.org/article/S0091-6749(14)01482-1/fulltext

Dust Mite Respiratory Allergy: current therapies http://buff.ly/1UwMMUJ - ALK PR company helped write the paper with 3 writers, open access.

No comments:

Post a Comment

Blog Widget by LinkWithin