Allergic rhinitis - top articles for April 2014

Here are my suggestions for some of the top articles about allergic rhinitis for April 2014:

FDA OKs Under-the-Tongue Oralair for Hay Fever: Due to the black box warning for anaphylaxis and death, all patients on Oralair must be prescribed an epinephrine auto-injector (requried by FDA) -- Allergist predicts: Oralair has little chance of success in the U.S. -- Due to anaphylaxis risk, any physician prescribing Oralair will be incurring a risk/liability. Injectable epinephrine should always be available for a person taking SLIT, including Oralair. It doesn't treat immediate symptoms -- months are required to realize benefits.

FDA asked for postapproval studies for Grastek's safety in children (5-11) due to lip swelling and oral blistering

Uncontrolled allergic rhinitis and chronic rhinosinusitis - EAACI position paper - US approach is slightly different

Validated questionnaire for atopy and from CDC:

Sensitization Rates in Young Germans: Big Numbers - Big Risks - Big Confusion

Skin prick test positivity to 1 or more allergens varied within Europe from 31% to 53% among adults

Daily SMS reminder improves adherence to medication and treatment outcomes in allergic rhinitis - 30-day study, in most studies the effect is lost after 90 days.

ARIA Guidelines for Allergic Rhinitis in General Practice: only 31% of GPs aware of guidelines, 10% implement them

Old, Wise and Allergic: Allergies Are No Longer Solely Diseases of the Grandchildren

Moving to a newly built home during infancy is associated with a considerable risk of rhinitis

Management of Contact Lens Wear in Patients With Ocular Allergy

Rhinitis increases risk of intermittent claudication in adults (RR 4), independently of the presence of atopy

Future treatments for allergic rhinitis as of 2014: anti-IgE omalizumab, histamine H3 & H4 receptor antagonists, toll-like receptors

Acupuncture for Allergies: limited benefit for allergic rhinitis symptoms, but benefit is short lived (8 weeks)

Specific immunoglobulin E (IgE) profile for 40 allergens using a novel microarray technique (BioIC): IgE sensitization to mites, pets, cockroaches, seafood, and cheese, is associated with elevated FeNO in children

Treatment Options for 
Allergic Rhinitis (AR) and 
Non-Allergic Rhinitis (NAR) in 6 Steps (click to enlarge the image).

The articles were selected from Twitter @Allergy and RSS subscriptions. Some of the top allergy accounts on Twitter contributed links. I appreciate the curation provided by @Aller_MD @AllergyNet @IgECPD @DrAnneEllis @AACMaven @AllergieVoeding @allergistmommy @mrathkopf @wheezemd.

Please feel free to send suggestions for articles to AllergyGoAway AT gmail DOT com and you will receive an acknowledgement in the next edition of this publication.

Image source: Wikipedia, Creative Commons license.

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