Macrolides for long-term management of asthma (meta-analysis): could be beneficial as adjunct asthma therapy

The effect of macrolides on FEV1 was not significant. However, there were improvements in peak expiratory flow, symptom scores, quality of life, and airway hyper-reactivity.
The study authors concluded that macrolides may be beneficial as adjunct asthma therapy. Future trials, focusing on long-term safety and effectiveness, should use standardized outcomes.
References:
Macrolides for the long-term management of asthma – a meta-analysis of randomized clinical trials. J. Reiter et al. Allergy, 2013.
http://onlinelibrary.wiley.com/doi/10.1111/all.12199/abstract
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