A study of 108 children examined the relationships between:
- sleep-disordered breathing (SDB, defined as intermittent nocturnal hypoxia and habitual snoring)
- asthma severity
Children aged 4-18 years (mean age 9 years) were recruited sequentially from a specialty asthma clinic. Asthma severity was determined after 1 year of follow-up and guideline-based treatment, 45% of patients were African-American; 68% male.
Obesity and sleep-disordered breathing (SDB) were common, affecting 43% and 30% of subjects, respectively.
Children with sleep-disordered breathing (SDB) had a 3.6-fold increased odds of having severe asthma at follow-up. Obesity was not associated with asthma severity.
Obesity, asthma, and sleep-disordered breathing are triangular protagonists.The coexistence of 2 or more of these disorders is common and carries a greater risk for worse outcomes. We need to determine if treating sleep-disordered breathing (SDB) improves asthma morbidity.
Sleep-Disordered Breathing is Associated with Asthma Severity in Children. The Journal of Pediatrics, Volume 160, Issue 5, Pages 736-742, May 2012.
Obesity, Asthma, and Sleep-Disordered Breathing. The Journal of Pediatrics, Volume 160, Issue 5 , Pages 713-714, May 2012 (full text)
Image source: A halo around the Moon. Wikipedia, GNU Free Documentation License.