360 patients with allergic rhinitis (AR) were evaluated in this Italian study:
- 66% had ”positive” results for bronchodilation test
- FEF25%−75% was abnormal in 21%
- 21% had severe BHR
An FEF25%−75% cutoff value of less than 58% of predicted may discriminate patients with both severe BHR and reversibility.
This study suggests a role of FEF25%−75% as a marker of early bronchial involvement in patients with persistent allergic rhinitis. FEF25%−75% value of less than 58% of predicted may suggest the co-existence of severe BHR and reversibility.
Relationship between bronchial hyperreactivity and bronchodilation in patients with allergic rhinitis. Giorgio Ciprandi, Alessio Signori, Ignazio Cirillo, Volume 106, Issue 6, Pages 460-466 (June 2011).
Resurrection men and the FEF25-75. JACI, 2010.
Image source: Spirometry, from Wikipedia, the free encyclopedia, GNU Free Documentation License.