Treatment of patients with primary immunodeﬁciency disease with IVIG is expensive.
The average product and administrative cost per infusion in physicians’ ofﬁces in the United States in 2005 was $2,075. This includes a product cost of $1,807 for 32 grams of IVIG and $268 in administrative costs for a 3-hour infusion.
If we adjust this data from 2005 to reﬂect consumer price index inﬂation we would expect the average infusion to cost approximately $2,262 (as of year 2008). At one infusion every four weeks, this represents an average annual cost of $29,406 per patient.
Antibody function: each antibody binds to a specific antigen; an interaction similar to a lock and key. Image source: Wikipedia.
Impact of intravenous immunoglobulin (IVIG) treatment among patients with Primary
Immunodeﬁciency diseases. Pharmaceuticals Policy and Law, 10 (2008), 133–146 (PDF).