What are the predictors of persistence of atopic dermatitis in adolescence?

German participants of the International Study of Asthma and Allergies in Childhood Phase II were followed prospectively. The dataset comprised 2857 adolescents.

The incidence of atopic dermatitis (AD) between ages 9-11 and 16-20 years was 1.7%, and recurrence was 2.4%.

AD persisted in 47.6% of adolescents with AD symptoms at baseline (n = 424).

What were the predictors of persistence of atopic dermatitis in adolescence?

- high socioeconomic status
- female sex
- asthma symptoms
- positive skin prick test response at baseline

- parental history of rhinitis/AD

- having worked in a high-risk job

With all the factors present, the probability of the incidence of AD was 21.4% and increased up to 81.7% for recurrence of AD and 87.6% for persistence of AD among those affected by AD.


Atopic Dermatitis Treatment - Illustrated (click here for full size image).

References:
Prediction of the incidence, recurrence, and persistence of atopic dermatitis in adolescence: A prospective cohort study. Peters AS, Kellberger J, Vogelberg C, Dressel H, Windstetter D, Weinmayr G, Genuneit J, Nowak D, von Mutius E, Radon K. J Allergy Clin Immunol. 2010 Sep;126(3):590-595.e3.