Epinephrine (adrenaline) Auto-Injectors in the U.S. include EpiPen, Twinject and now Adrenaclick

Epinephrine (adrenaline) Auto-Injectors in the U.S. include EpiPen, Twinject and now Adrenaclick (http://www.adrenaclick.com).

EpiPen and Twinject are available as double units (2 doses) but Adrenaclick comes only in single units (1 dose) for now. Adrenaclick is a single dose of epinephrine in otherwise the same delivery device as Twinject.

Twinject (2 units) and Adrenaclick (1 unit) are actually made by the same company for epinephrine auto-injectors, Sciele Pharma. The company is based in Atlanta, Georgia with offices in the U.S. and Japan, where the parent conglomerate is located.


Video: Anaphylaxis and Your Epi Pen. Allergy and Asthma Clinics of Georgia.

Pricing for Epineprhine Auto-Injectors (U.S.)

Epipen
http://www.epipen.com
Manufacturer: Dey Laboratories
0.3 mg (for patients 66 lb and over, more than 30 kg) and 0.15 mg (for patients 33 lb to 66 lb, 15-30 kg)

Epipen
0.3 MG/0.3ML (1:1000) (1 syringe): $65.04
0.3 MG/0.3ML (1:1000) (1 package, 2 ea): $121.80

Epipen Jr
0.15 MG/0.3ML (1:2000) (1 syringe): $64.99
0.15 MG/0.3ML (1:2000) (1 package, 2 ea): $115.49

EpiPen, EpiPen Jr, EpiPen 2-Pak, and EpiPen Jr 2-Pak are all registered trademarks of Dey, L.P.

Twinject
http://www.twinject.com
Manufacturer: Sciele Pharma, Inc.

0.3 MG/0.3ML (1:1000) (1 package, 1 device, 2 doses)
0.15 MG/0.3ML (1:2000) (1 package, 1 device, 2 doses)
$99.99 each

Twinject may also be prescribed as a Two-Pack, which includes 2 Twinject auto-injectors.

Adrenaclick (pronounced, "a-dren-a-click")
http://www.adrenaclick.com
Manufacturer: Sciele Pharma, Inc. (same as Twinject)
Single unit or a Two-Pack (Two-Pack to be available later)
Two dosing options (0.15 mg and 0.3 mg)
Pricing not yet available, more information after February 2010 at http://www.adrenaclick.com

The double-dose devices are called 2-Pak for EpiPen and Two-Pack for Twinject.

Related videos from YouTube:
Epi-Pen and Epi-Pen Trainer Video. Leslea Harmon of allergyware.com.
How to use the Twinject injector. Leslea Harmon of allergyware.com.
How to use a Twinject. OnlineAllergist.
Medication - Epipen. Michael Marcus, MD.
Anaphylaxis and Your Epi Pen Training Video. Allergy and Asthma Clinics of Ga.
Using Epipen. Gerryyen.
Epipen usage in children. Michael Marcus, MD

References:
What are the ‘ideal’ features of an adrenaline (epinephrine) auto-injector in the treatment of anaphylaxis? http://goo.gl/lxCh
Figure: Design overview of currently available auto-injectors for emergency self-administration of adrenaline in the treatment of anaphylaxis.
Training of trainers on epinephrine autoinjector use increases correct use from 23.3% to 74.2% http://goo.gl/lMfSR

1 comment:

  1. Anonymous1/30/2010

    Per the information sent to me by FAAN (Jan 30, 2010) Adrenaclick is available in a two-pack.

    ReplyDelete