EpiPen and Twinject are available as double units (2 doses) but Adrenaclick comes only in single units (1 dose) for now. Adrenaclick is a single dose of epinephrine in otherwise the same delivery device as Twinject.
Twinject (2 units) and Adrenaclick (1 unit) are actually made by the same company for epinephrine auto-injectors, Sciele Pharma. The company is based in Atlanta, Georgia with offices in the U.S. and Japan, where the parent conglomerate is located.
Video: Anaphylaxis and Your Epi Pen. Allergy and Asthma Clinics of Georgia.
Pricing for Epineprhine Auto-Injectors (U.S.)
Manufacturer: Dey Laboratories
0.3 mg (for patients 66 lb and over, more than 30 kg) and 0.15 mg (for patients 33 lb to 66 lb, 15-30 kg)
0.3 MG/0.3ML (1:1000) (1 syringe): $65.04
0.3 MG/0.3ML (1:1000) (1 package, 2 ea): $121.80
0.15 MG/0.3ML (1:2000) (1 syringe): $64.99
0.15 MG/0.3ML (1:2000) (1 package, 2 ea): $115.49
EpiPen, EpiPen Jr, EpiPen 2-Pak, and EpiPen Jr 2-Pak are all registered trademarks of Dey, L.P.
Manufacturer: Sciele Pharma, Inc.
0.3 MG/0.3ML (1:1000) (1 package, 1 device, 2 doses)
0.15 MG/0.3ML (1:2000) (1 package, 1 device, 2 doses)
Twinject may also be prescribed as a Two-Pack, which includes 2 Twinject auto-injectors.
Adrenaclick (pronounced, "a-dren-a-click")
Manufacturer: Sciele Pharma, Inc. (same as Twinject)
Single unit or a Two-Pack (Two-Pack to be available later)
Two dosing options (0.15 mg and 0.3 mg)
Pricing not yet available, more information after February 2010 at http://www.adrenaclick.com
The double-dose devices are called 2-Pak for EpiPen and Two-Pack for Twinject.
Related videos from YouTube:
Epi-Pen and Epi-Pen Trainer Video. Leslea Harmon of allergyware.com.
How to use the Twinject injector. Leslea Harmon of allergyware.com.
How to use a Twinject. OnlineAllergist.
Medication - Epipen. Michael Marcus, MD.
Anaphylaxis and Your Epi Pen Training Video. Allergy and Asthma Clinics of Ga.
Using Epipen. Gerryyen.
Epipen usage in children. Michael Marcus, MD
What are the ‘ideal’ features of an adrenaline (epinephrine) auto-injector in the treatment of anaphylaxis? http://goo.gl/lxCh
Figure: Design overview of currently available auto-injectors for emergency self-administration of adrenaline in the treatment of anaphylaxis.
Training of trainers on epinephrine autoinjector use increases correct use from 23.3% to 74.2% http://goo.gl/lMfSR