Antioxidants for treatment of allergic rhinitis

Oxidative stress plays a causative role in upper airway inflammation.

Antioxidant therapies for airway inflammation may be grouped into 3 categories:

- endogenous metabolic agents
- vitamins/nutrients
- botanical extracts

Studies examining effects in upper airway inflammation are limited and primarily consist of in-vitro human and in-vivo animal models.

Human studies suggest that subpopulations affected by specific genetic, environmental, dietary factors are most likely to benefit from antioxidant therapy.

My opinion: It is too early to tell. More studies are needed but this is an area that one can keep an eye on.

Novel antioxidant approaches to the treatment of upper airway inflammation. Braskett M, Riedl MA. Curr Opin Allergy Clin Immunol. 2009 Nov 20. [Epub ahead of print].
Image source: Space-filling model of the antioxidant metabolite glutathione. Wikipedia, public domain.

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