Deficiency of circulating plasmacytoid dendritic cells (pDC) during infancy appears to be a risk factor for asthma. Infants with higher numbers of circulating plasmacytoid dendritic cells (pDC) appear "protected" against asthma http://bit.ly/2xUexA
The minimally important difference in Asthma Control Test (ACT) used for comparison between test samples is 3 points http://bit.ly/hv04A
Inhibition of IL-4–STAT6 might explain the mechanism of aspirin desensitization http://bit.ly/13A9v2
People who clean their homes with bleach are less likely to be atopic but more likely to have respiratory symptoms. http://bit.ly/nMAAj
Immunotherapy studies have demonstrated that a local reaction does not predict a systemic reaction. Local reactions to immunotherapy do not predict local reactions at the next immunotherapy injection. http://bit.ly/WYTgN
Factors associated with uncontrolled asthma were different in ICS users and non-ICS users. In ICS users: chronic cough/phlegm, female sex. Factors associated with uncontrolled asthma in non-ICS users: high total IgE and sensitization to molds http://bit.ly/unKon
There is a need for better designed sublingual immunotherapy (SLIT) clinical trials. Several unpublished oral and sublingual immunotherapy studies in the United States failed to meet primary endpoints. http://bit.ly/ttaIB
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