Rate of adherence to subcutaneous immunotherapy (SCIT) is low, at less than 70%. The possible explanations for that fact include the following factors:
- inconvenience
- lack of perceived efficacy
- costs and loss of working hours
In comparison, local nasal immunotherapy has a even lower adherence rate (27%), due to the local nasal side effects.
For sublingual immunotherapy (SLIT), the rates of compliance are greater than 75%.
The reasons for discontinuation of SLIT are:
- costs
- inconvenience
- feeling of inefficacy
- side effects
In real life, costs and patient education are crucial issues in adherence to this SCIT and SLIT. Reduction of costs and more efforts in education of patients may improve the adherence to immunotherapy.
References:
Evidence of adherence to allergen-specific immunotherapy. Senna G, Ridolo E, Calderon M, Lombardi C, Canonica GW, Passalacqua G. Curr Opin Allergy Clin Immunol. 2009 Dec;9(6):544-8.
SCIT ("allergy shots") is at least as potent as pharmacotherapy in controlling the symptoms of allergic rhintis as early as the first season of therapy. JACI, 2011.
Image source: OpenClipArt.org, public domain.
Image source: OpenClipArt.org, public domain.
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