Some statistical methods used in allergy and immunology research

Example: Clinical efficacy and immune regulation with peanut oral immunotherapy. Jones SM et al. J Allergy Clin Immunol. 2009 Jul 2.

ANOVA shows if the means of several groups are all equal, generalizes Student's 2-sample t-test to more than 2 groups

Factorial ANOVA is used when the experimenter wants to study the effects of two or more treatment variables

In mixed-design ANOVA, one factor is a between-subjects variable and the other is within-subjects variable

A mixed model is a statistical model containing both fixed effects and random effects.

Restricted maximum likelihood is a method for fitting linear mixed models

Wilcoxon signed-rank test is a non-parametric test for 2 related samples or repeated measurements on a single sample

Wilcoxon signed-rank test can be used as alternative to paired Student's t-test when population cannot be assumed to be normally distributed. Mann-Whitney-Wilcoxon is a variant of Wilcoxon signed-rank test for 2 independent samples

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