What is TaqMan?

Example: Clinical efficacy and immune regulation with peanut oral immunotherapy. Jones SM et al. J Allergy Clin Immunol. 2009 Jul 2.

JAK-STAT (Janus kinase-signal transducer and activator of transcription) path transmits signals directly to target gene. JAK-STAT signaling is evolutionarily conserved in eukaryotic organisms from slime molds to humans http://bit.ly/16yaNe

cDNA is a complementary DNA synthesized from a mature mRNA template by the enzyme reverse transcriptase http://bit.ly/V5Jmv

TaqMan are hydrolysis probes used to increase the specificity of real-time PCR assays. TaqMan principle relies on the 5´–3´ nuclease activity of Taq polymerase and fluorophore-based detection. TaqMan probes were named after the videogame PacMan (Taq Polymerase + PacMan = TaqMan) http://bit.ly/15UwMT

Taq polymerase is a DNA polymerase named after thermophilic bacterium Thermus aquaticus from which it was isolated http://bit.ly/52a2b

Taqman in Molecular diagnostic PCR handbook By Gerrit J. Viljoen, L. H. Nel, J. R. Crowther:

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