JACI: Advances in basic and clinical immunology in 2008

- Modulation of T(H)2 responses by specific transcription factors and receptors associated with the innate immunity - for example a TLR-9 agonist

- HIV-infected individuals who receive antiviral treatment develop a high incidence of asthma, resembling the inflammatory processes associated with immunoreconstitution

- Correlation of molecular diagnosis and clinical presentation was analyzed in 4 rare primary immunodeficiencies (PID): hyper-IgE syndrome; immune dysfunction, polyendocrinopathy, enteropathy, X-linked disease; cartilage-hair hypoplasia; and nuclear factor-kappaB essential modulator deficiency

- Long-term outcomes from patients with severe combined immunodeficiency (SCID) who received bone marrow transplants (BMT) considered successful


Severe combined immunodeficiency (SCID) - 4 groups according to T/B/NK cells (click to enlarge the image).

References:
Advances in basic and clinical immunology in 2008. Chinen J, Shearer WT. J Allergy Clin Immunol. 2009 Feb;123(2):328-332.
Advances in Allergy and Immunology. JACI.
Image source: Wikipedia, GNU Free Documentation License.

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