41 positive patch tests were found in 6% of patients.
- emollients (47%)
- chlorhexidine (42%)
- hexamidine (7.5%)
- tixocortol pivalate and bufexamac (2.5% each)
Risk factors associated with sensitization to AD treatment were:
- AD severity
- AD onset before the age of 6 months
- IgE-mediated sensitization
The authors concluded that topical treatments for AD are associated with cutaneous sensitization. Antiseptics and emollients represent the most frequent sensitizers.
Atopic Dermatitis Treatment - Illustrated (click to enlarge the image).
Prevalence and risk factors for allergic contact dermatitis to topical treatment in atopic dermatitis: a study in 641 children. Mailhol C, Lauwers-Cances V, Rancé F, Paul C, Giordano-Labadie F. Allergy. 2009 Jan 29.
Image source: Moisturizer, White Petrolatum (vaseline), Wikipedia, GNU Free Documentation License.