JACI: Advances in allergic skin disease, anaphylaxis, and hypersensitivity reactions to foods, drugs, and insects in 2008

- a rise in anaphylaxis in a population-based study

- lower rates of peanut allergy in Israel, where infants consume peanut products early

- IgE epitope mapping that discloses the likelihood and severity of allergy

- correlating likelihood of clinical reactivity with food-specific IgE to sesame, peanut, milk, and tree nuts

- majority of children with milk and egg allergy tolerate these proteins in modest amounts when they are extensively heated in baked goods

- promise for oral immunotherapy to treat milk allergy and sublingual immunotherapy for honey bee venom hypersensitivity

- skin barrier dysfunction is important in the pathophysiology of atopic dermatitis (AD)

- immunologic defects contribute to the propensity of patients with AD to develop viral and bacterial infection

References:
Advances in allergic skin disease, anaphylaxis, and hypersensitivity reactions to foods, drugs, and insects in 2008. Sicherer SH, Leung DY. J Allergy Clin Immunol. 2009 Feb;123(2):319-327.

1 comment:

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