Gammagard Liquid is the first 10% IVIG solution with no added carbohydrates or sodium. Baxter is replacing Gammagard S/D with Gammagard Liquid.
Gammagard: No added sodium. When reconstituted with the total volume of diluent (Sterile Water for Injection, USP) supplied to 5%, Gammagard contains a physiological concentration of sodium chloride (approximately 8.5 mg/mL) and has a pH of 6.8 ± 0.4.
Octagam: sodium content of the final solution is ≤ 30 mmol/l and the pH is between 5.1 and 6.0.
Gammagard osmolality is 240-300 mOsmol/kg, similar to physiological osmolality (285 to 295 mOsmol/kg).
Octagam osmolality is 310 - 380 mosmol/kg.
Gammagard Liquid, Baxter, $129.60/gm
Octagam, Octapharma, $118.34/gm
Prices represent cost per unit specified and are representative of "Average Wholesale Price" (AWP).