How common are reactions to pneumococcal vaccine in pediatrics?

Overdiagnosis of vaccine allergy is a major public health problem

The 23-valent-polysaccharide pneumococcal vaccine (PPV23) is recommended for patients at high risk for invasive disease from Streptococcus pneumoniae and is also used in the evaluation of patients with suspected immunodeficiency.

In a chart review of 173 pediatric patients, local reactions to PPV23 occurred in 50% of recipients. Systemic reactions only occurred in 1% of recipients.

Systemic reaction to pneumococcal vaccine: How common in pediatrics? Yousef, Ejaz; Mannan, Susan. Allergy and Asthma Proceedings, Volume 29, Number 4, 7/8 2008 , pp. 397-399(3).
Image source: Streptococcus pneumoniae from Wikipedia, the free encyclopedia, public domain.

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