According to a Finnish study of 6,000 children, there was a significant association between high birth weight (bigger than 4,5 kg) and atopy and asthma.
The biological mechanisms behind the associations are unknown, but they could be related to obesity.
References:
High birth weight, asthma and atopy at the age of 16 yr. T. Remes et al. Pediatric Allergy and Immunology (OnlineEarly Articles). doi:10.1111/j.1399-3038.2007.00707.x
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