New Articles about Allergic Rhinitis

Herbal medicines for the treatment of allergic rhinitis: a systematic review.
Ruoling Guo et al. Annals of Allergy, Asthma and Immunology, 01/2008.

According to the authors, there is encouraging evidence suggesting that P hybridus (Butterbur) may be an effective herbal treatment for seasonal (intermittent) AR. There are also promising results generated for other herbal products, particularly Aller-7, Tinospora cordifolia, Perilla frutescens, and several Chinese herbal medicines. Confirmation in larger and rigorously designed clinical trials is warranted.

Safety and tolerability of fexofenadine hydrochloride, 15 and 30 mg, twice daily in children aged 6 months to 2 years with allergic rhinitis.
Frank C. Hampel et al. Annals of Allergy, Asthma and Immunology, 01/2008.

Which antihistamine to use in young children? Antihistamines are first-line treatment for allergic rhinitis and are widely prescribed in infants for allergic symptoms but their safety profile in very young children is not well-established. Fexofenadine (Allegra) given for a mean duration of 8 days was well tolerated, with a good safety profile, in the study population of children aged 6 months to 2 years.

Pathophysiology and progression of nasal septal perforation.
Bobby Lanier et al. Annals of Allergy, Asthma and Immunology, 01/2008.

What are the causes of nasal septal perforation? The article lists different causes of nasal septal perforation (NSP): piercings, exposure to industrial chemicals, illicit drug use, intranasal steroid use, surgical trauma, bilateral cautery, and possibly improper use of nasal applicators.

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