Berci Mesko of ScienceRoll.com interviewed John Routes from the Children’s Hospital of Wisconsin about the screening for Severe Combined Immune Deficiency (SCID), sometimes called “Bubble Boy Disease.”
SCID is a heterogeneous group of genetic disorders characterized by an arrest in T lymphocyte development which leads to an abnormal differentiation of B and NK cells.
Severe combined immunodeficiency: A cohort of 40 patients in Iran. Mehdi Yeganeh et al. Pediatric Allergy and Immunology (OnlineEarly Articles). doi:10.1111/j.1399-3038.2007.00647.x
The state of Wisconsin approach to newborn screening for SCID: 5 infants with SCID detected in 3 years. JACI, 2012.