Researchers evaluated asthmatic patients with high IgE levels (higher than 100 IU/mL) and compared them to patients with asthma with low IgE levels (less than 100).
Patients with high IgE had a lower FEV1, forced expiratory flow, and FEV1/forced vital capacity. In addition, 55% of patients with high IgE had been previously hospitalized, compared with 44% of patients with asthma with low IgE.
In conclusion, IgE level may be inversely correlated with baseline lung function and asthma severity.
In the Clinic - Dr. Robert Wood, MD, Discusses the IgE Blood Allergy Test |
Dr. Robert Wood, MD, Discusses the IgE Blood Allergy Test. InsiderMedicine.ca (video).
Severe asthma - differential diagnosis and management (click to enlarge the image).
References:
Association between IgE levels and asthma severity among African American, Mexican, and Puerto Rican patients with asthma. Mariam Naqvi at al. JACI, Volume 120, Issue 1, Pages 137-143 (July 2007).
Image source: Wikipedia, public domain.
Related:
In the Clinic - Dr. Robert Wood, MD, Discusses the IgE Blood Allergy Test. InsiderMedicine.ca (video).
Updated: 01/10/2008
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